Wednesday, 18 January 2017

ANTI HYPERTENSIVE DRUGS

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ANTI HYPERTENSIVE DRUGS:

Anti Hypertensive Drugs are used to treat Hypertension, Hypertension is a condition in which the systolic blood pressure is more than 140 mm Hg or a diastolic blood pressure is more than  90 mm Hg.



List of Following drugs are used to Management the Hypertension:

ANTIADRENERGIC & CENTRALLY ACTING AGENTS
Rauwolfia alkaloids
Rescinnamine
Reserpine
Deserpidine  
Bietaserpine      
Methoserpidine        

Methyldopa

Imidazoline receptor agonists
Guanfacine
Clonidine
Tolonidine
Moxonidine
Rilmenidine

ANTIADRENERGIC AGENTS, GANGLION-BLOCKING 
Sulfonium derivatives
Trimetaphan

Secondary and tertiary amines
Mecamylamine

ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 
Alpha-adrenoreceptor antagonists
Prazosin
Doxazosin
Urapidil 
Indoramin
Trimazosin

Guanidine derivatives
Betanidine
Guanoclor
Guanoxan
Debrisoquine
Guanazodine
Guanoxabenz
Guanethidine  

DRUGS ACTING ON ARTERIOLAR SMOOTH MUSCLE
Thiazide derivatives
Diazoxide

Hydrazinophthalazine derivatives
Hydralazine
Endralazine
Cadralazine 
Dihydralazine

Pyrimidine derivatives
Minoxidil

Nitroferricyanide derivatives
Nitroprusside

Guanidine derivatives
Pinacidil

OTHER ANTIHYPERTENSIVES 
Alkaloids other than Rauwolfia
Veratrum

MAO inhibitors
Pargyline 

Serotonin antagonists
Ketanserin 

Tyrosine hydroxylase inhibitors
Metirosine

Antihypertensives agents for pulmonary arterial hypertension
Bosentan
Macitentan
Riociguat
Ambrisentan
Sitaxentan

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