Monday, 29 July 2019

HOW TO START JANAUSHADHI KENDRA IN INDIA

Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) is Central Govt of India scheme to Provide Quality medicines to the Indian citizens at affordable price. It’s a good opportunity to the Unemployed Pharmacist or others who are interested to open a Pharmacy store, generally the following steps are involved in the process of establishing a pharmacy store.
1.     Need to select the place or area where the store can be opened
2.     Need to upload the details on http://janaushadhi.gov.in/
3.     You will get the mail from the Bureau of Pharma PSUs of India (BPPI) or the Respective team
4.     Once You received the email, you need to approach the Drug inspector along with the print of the mail which you received from BPPI and also you will get the state marketing officer number on the mail for further guidelines you can also contact him
5.     Produce the required documents to the Drug inspector office
6.     Drug inspectors generally visit the store; check the premises and equipment which are to be kept as per Schedule N of Drug and Cosmetic Act.
7.     After a few days or week, you will receive the license copy if the Drug inspector is satisfied on the visit
8.     Once you received the license copy, you need to sign on MOU with BPPI on bond paper, the same has been scanned and mailed to the BPPI and you have to courier the hard copies to the BPPI Office.
9.     Once the BPPI office receive your details, BPPI people will call you and allot a store code, install the software through Team-viewers or related applications
10.  Once the software installed you can place the order and upon receiving the stock you can sell the products from your store

Tuesday, 31 January 2017

Different Types of Vaccines

Vaccines:
Vaccines are prepared to use as the Preventive inoculation to develop Immunity against targeted Disease, like Poliomyelitis.
This preparation contains Killed or Weakened Bacteria or Viruses, Which act as Antigen, this antigen starts activating Immune System to develop respective Antibody.

When the Actual Bacteria or Virus Enter into the body the Immune System Identify the Bacteria, Virus or Its metabolites/ its related proteins, which act as Antigen and this antigen will be Identified by Immune System and Antibodies will be released, With help of this Immune Cell (Antibodies) and other cells from Complementary System together kill the Bacteria,Virus or Its related Particles.

Following are the classification of Vaccines:

Bacterial vaccines
Anthrax vaccines
Brucellosis vaccines
Cholera vaccines
Diphtheria vaccines
Haemophilus influenza B vaccines
Meningococcal vaccines
Pertussis vaccines
Plague vaccines
Pneumococcal vaccines
Tetanus vaccines
Tuberculosis vaccines
Typhoid vaccines
Typhus (exanthematicus) vaccines

Viral vaccines
Encephalitis vaccines
Influenza vaccines
Hepatitis vaccines
Measles vaccines
Mumps vaccines
Poliomyelitis vaccines
Rabies vaccines
Rotavirus diarrhea vaccines
Rubella vaccines
Varicella zoster vaccines
Yellow fever vaccines
Papillomavirus vaccines

Combination Of Bacterial and viral vaccines
Diphtheria-poliomyelitis-tetanus
Diphtheria-pertussis-poliomyelitis-tetanus
Diphtheria-rubella-tetanus
Hemophilus influenza B and poliomyelitis
Diphtheria-hepatitis B-pertussis-tetanus
Diphtheria-Hemophilus influenza B-pertussis-poliomyelitis-tetanus
Diphtheria-hepatitis B-tetanus
Hemophilus influenza B and hepatitis B
Diphtheria-Haemophilus influenza B-pertussis-poliomyelitis-tetanus-hepatitis B
Typhoid-hepatitis A
Diphtheria-Hemophilus influenza B-pertussis-tetanus-hepatitis B
Diphtheria-pertussis-poliomyelitis-tetanus-hepatitis B
Diphtheria-Haemophilus influenza B-pertussis-tetanus-hepatitis B-meningococcus A + C

Sunday, 22 January 2017

DIABETES MELLITUS

Type 1 Diabetes Mellitus (DM 1):

In Type I DM the production of insulin by the pancreatic is reduced or completely absent, hence the required amount of Insulin for biological need is reduced which results in Type I DM.

Cause: It is an Auto Immune Disorder, in which the pancreatic cells are destroyed by his or her own Immune System, Which results in lack of insulin Production, which interns result in Type I DM

Following classes of Drugs are used to Management or Treatment of Type I DM
INSULIN AND ANALOGUES
Fast Acting- For Injection:
Insulin (human)
Insulin lispro
Insulin aspart
Insulin glulisine
Insulin (beef)
Insulin (pork)

Intermediate-acting- For Injection:
Insulin (human)
Insulin lispro
Insulin (beef)

Insulin (pork)
Intermediate- or long-acting combined with fast-acting - For Injection:
Insulin (human)
Insulin lispro
Insulin aspart
Insulin degludec and insulin aspart
Insulin (beef)
Insulin (pork)

Long-acting - For Injection:
Insulin (human)
Insulin glargine
Insulin detemir
Insulin degludec
Insulin degludec and liraglutide
Insulin (beef)
Insulin (pork)

Insulin and analogues for inhalation
Insulin (human)

Type 2 Diabetes: 

It is a most common type of Diabetes mellitus, its gradually increasing form of Diabetes mellitus.

Causes: Lifestyle and Genetic mutation are the two major cause of Diabetes mellitus. The basic fact of the cause of Diabetes mellitus is Resistance developed to the sensitivity of Insulin. Insulin is the one most important hormone to control the blood glucose levels by promoting the utilization of glucose.

Following class of drugs are used to manage or treat the symptoms of type 2 diabetes mellitus

Biguanides
Metformin
Phenformin
Buformin 

Sulfonylureas
Glipizide
Gliquidone 
Gliclazide 
Glibenclamide
Chlorpropamide
Glisoxepide
Glimepiride
Acetohexamide
Carbutamide
Tolbutamide
Glibornuride
Tolazamide
Metahexamide

Sulfonamides (heterocyclic)
Glymidine

Alpha glucosidase inhibitors
Acarbose
Voglibose        
Miglitol

Thiazolidinediones
Troglitazone
Pioglitazone
Rosiglitazone

Dipeptidyl peptidase 4 (DPP-4) inhibitors
Saxagliptin
Alogliptin 
Sitagliptin
Vildagliptin
Linagliptin
Gemigliptin
Sitagliptin and Simvastatin        

Glucagon-like peptide-1 (GLP-1) analogues
Exenatide
Albiglutide
Lixisenatide
Dulaglutide 
Liraglutide

Sodium-glucose co-transporter 2 (SGLT2) inhibitors
Canagliflozin
Dapagliflozin
Empagliflozin

Other blood glucose lowering drugs, excl. insulins
Guar gum    
Mitiglinide    
Pramlintide
Benfluorex 
Repaglinide
Nateglinide

Saturday, 21 January 2017

CAREER

Pharmaceutical science is a Comprehensive study of Medical science and Engineering, it includes core subjects like Pharmaceutical Technology, Pharmaceutical Analysis, Pharmacology, Pharmaceutical Biotechnology, Pharmaceutical Chemistry, Pharmacognosy and Regulatory Affairs. 
for the completion of Bachelor of Pharmacy has to clear nearly 21 Subjects and 18 labs.

There are many kinds of job openings are available for Pharma Graduates and Post Graduates, In Govt Sectors jobs like Drug Inspectors, Analyst, Pharmacist, Faculty in various Govt colleges and Universities, CDSCO and PIC dept.

In private also a huge number of jobs openings are available like Pharmacist, Clinical Pharmacist, Production chemist to Manager, Quality Assurance dept., Quality control dept., Regulatory Affairs dept., Marketing Dept. and Pharmacovigilance and Medical writing.

For those who wants to start their career in pharma sector should has good knowledge of Pharma and its related information.

Friday, 20 January 2017

CARDIAC GLYCOSIDES

Heart Failure (HF) is a result of complex, progressive disorder in which the heart is not able to pump required amount of blood to overcome the body needs for its physiological functions.

There are many classes of drugs are available to manage or treat the Heart failure, Cardiac glycosides are one of those class of Drugs, it includes following list of drugs:


CARDIAC GLYCOSIDES:
Digitalis glycosides
Digoxin
Acetyldigitoxin
Digitoxin
Lanatoside C
Deslanoside
Metildigoxin
Gitoformate      
Digitalis leaves  

Scilla glycosides
Proscillaridin

Strophanthus glycosides
G-strophanthin
Cymarin

Other cardiac glycosides
Peruvoside

Wednesday, 18 January 2017

ANTI HYPERTENSIVE DRUGS

ANTI HYPERTENSIVE DRUGS:

Anti Hypertensive Drugs are used to treat Hypertension, Hypertension is a condition in which the systolic blood pressure is more than 140 mm Hg or a diastolic blood pressure is more than  90 mm Hg.



List of Following drugs are used to Management the Hypertension:

ANTIADRENERGIC & CENTRALLY ACTING AGENTS
Rauwolfia alkaloids
Rescinnamine
Reserpine
Deserpidine  
Bietaserpine      
Methoserpidine        

Methyldopa

Imidazoline receptor agonists
Guanfacine
Clonidine
Tolonidine
Moxonidine
Rilmenidine

ANTIADRENERGIC AGENTS, GANGLION-BLOCKING 
Sulfonium derivatives
Trimetaphan

Secondary and tertiary amines
Mecamylamine

ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING 
Alpha-adrenoreceptor antagonists
Prazosin
Doxazosin
Urapidil 
Indoramin
Trimazosin

Guanidine derivatives
Betanidine
Guanoclor
Guanoxan
Debrisoquine
Guanazodine
Guanoxabenz
Guanethidine  

DRUGS ACTING ON ARTERIOLAR SMOOTH MUSCLE
Thiazide derivatives
Diazoxide

Hydrazinophthalazine derivatives
Hydralazine
Endralazine
Cadralazine 
Dihydralazine

Pyrimidine derivatives
Minoxidil

Nitroferricyanide derivatives
Nitroprusside

Guanidine derivatives
Pinacidil

OTHER ANTIHYPERTENSIVES 
Alkaloids other than Rauwolfia
Veratrum

MAO inhibitors
Pargyline 

Serotonin antagonists
Ketanserin 

Tyrosine hydroxylase inhibitors
Metirosine

Antihypertensives agents for pulmonary arterial hypertension
Bosentan
Macitentan
Riociguat
Ambrisentan
Sitaxentan